Florence vs Greenville: Medical Assistant Salary (2026)
Compare medical assistant salaries between Florence, SC and Greenville, SC. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | Florence, SC | Greenville, SC |
|---|---|---|
| Median Salary | $40,718 | $47,090▲ |
| Hourly Rate | $19.58 | $22.64▲ |
| Entry Level (P10) | $35,606 | $36,561▲ |
| 25th Percentile | $38,367 | $39,290▲ |
| 75th Percentile | $48,024 | $49,693▲ |
| Top Earner (P90) | $50,459 | $51,572▲ |
| Total Employed | 420 | 2,550▲ |
Verdict
Greenville, SC offers better overall compensation for medical assistants, winning 4 out of 4 metrics compared to Florence.
The salary gap between Florence and Greenville is $6,372 (15.65%). Greenville's median is -1.82% compared to the US national median of $47,961.
Salary Range Comparison
The full salary range (10th to 90th percentile) in Florence spans $14,853,Greenville spans $15,011. Greenville has a wider pay range, suggesting more variation in pay between entry-level and experienced medical assistants.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, Greenville ($50,493 effective) pays 7.61% more than Florence ($46,924 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose Florence if…
- ✓You prefer the South Carolina area and lifestyle
Choose Greenville if…
- ✓Higher median salary ($47,090/year)
- ✓Better top-earner potential ($51,572)
- ✓Larger job market (2,550 employed)
- ✓Better purchasing power (CoL-adjusted: $50,493)
- ✓You prefer the South Carolina area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, medical assistant salaries in Florence grew 42.6% from 2019 to 2025, compared to 42.1% growth in Greenville over the same period.
Florence, SC
$27,210 (2019) → $38,790 (2025)
Greenville, SC
$31,570 (2019) → $44,860 (2025)
View Full Salary Data
Florence, SC
Greenville, SC
Frequently Asked Questions
Which city pays medical assistants more: Florence or Greenville?
What is the hourly rate difference between Florence and Greenville?
Should I relocate from Florence to Greenville as a medical assistant?
What do entry-level medical assistants earn in Florence vs Greenville?
Written by Emma Chen, CMA
Career Analyst
Emma has over 8 years of experience as a medical assistant. She has worked in both outpatient clinics and hospitals. Her expertise includes patient care and administrative support.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 4.97% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Emma Chen, CMA, a licensed medical assistant with 10+ years of clinical experience. · View source data at BLS.gov