Medical Assistant Salary in Greenville, SC: $47,090 (2026)
Quick Answer:A full-time medical assistant in Greenville, SC earns a median $47,090/year (≈ $22.64/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 31-9092). Once you factor in Greenville's price level (7% below national, BEA RPP 93.3), that paycheck buys what $50,493 would nationally. Nominal pay sits 9.8% above the South Carolina state average.
Official BLS data · View source
In 2026, professionals in the medical assistant field in Greenville, South Carolina will see median annual earnings around $47,090, slightly trailing the national figure of $47,961. The salary range for medical assistants in this region is projected to vary from $36,561 at the lower tenth percentile to $51,572 at the upper ninetieth percentile. This information is based on 2025 BLS OEWS data, projected to 2026, reflecting the job market's growing demand for skilled medical assistants as they bridge towards nursing roles. With a current employment base of 2,550 medical assistants, Greenville offers significant opportunities, especially for those considering pathways that lead to LPN or RN certification, enhancing long-term career potential.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $36,561 | $17.57 |
| Lower Range (P25) | $39,290 | $18.88 |
| Median (P50)(typical) | $47,090 | $22.64 |
| Upper Range (P75) | $49,693 | $23.89 |
| Top Earners (P90) | $51,572 | $24.79 |
Median Salary Position
1.82% below the national average
2026 Salary Percentile Distribution in Greenville
In Greenville, SC, the medical assistant salary spread from the 10th to 90th percentile is $15,011 (2026 est.). At $47,090, the local median is 1.82% below the national median of $47,961.
Salary Calculator
At 40 hours/week in Greenville: You'd be above the median
How Greenville Medical Assistant Pay Compares
Greenville median: $47,090/year (2026)
| Compared To | Median Salary | Greenville Pays |
|---|---|---|
| South Carolina Average | $42,887 | +9.80% more |
| National Average | $47,961 | -1.82% less |
Medical Assistants in Greenville, SC earn a median of $47,090 per year (2026 est.), which is 1.82% lower than the national median of $47,961 and 9.80% above the South Carolina state average of $42,887.
Cost-of-Living Adjusted Salary
Greenville has a cost of living 6.74% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Greenville, SC has a cost-of-living index of 93.26 (below the national average of 100). A medical assistant earning $47,090 nominally has purchasing power equivalent to $50,493 in an average-cost city — an effective 7.23% boost.
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2019 BLS Actual
$31,570
2025 BLS Actual
$44,860
2026 Current Est.
$47,090
2019–2027 Growth
+56.6%
Salary Trajectory for Medical Assistants in Greenville (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 4.97% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $31,570 | Actual |
| 2020 | $32,170 | Actual |
| 2021 | $36,330 | Actual |
| 2022 | $36,570 | Actual |
| 2023 | $38,250 | Actual |
| 2024 | $39,210 | Actual |
| 2025 | $44,860 | Actual |
| 2026(current) | $47,090 | Estimated |
| 2027 | $49,430 | Projected |
Based on 7 years of BLS OEWS data for the Greenville metropolitan area, the median medical assistant salary grew 42.1% from $31,570 (2019) to $44,860 (2025). At a 4.97% compound annual growth rate, salaries are projected to reach $49,430 by 2027 — a total increase of $17,860 (56.57%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Greenville metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 4.97% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $36,561 – $39,290 |
| 3-5 years (Mid Career) | $39,290 – $47,090 |
| 5+ years (Experienced) | $47,090 – $49,693 |
| 10+ years (Top Earner) | $49,693 – $51,572 |
MA, CMA salary ranges estimated from BLS percentile data. Individual medical assistant compensation varies by employer, certifications, and specialization.
Medical Assistant Job Market in Greenville
While the projected salary for medical assistants in Greenville SC is competitive, the cost of living index at 93.26 indicates that take-home pay may stretch further than in areas with higher costs. Medical assistant pay in Greenville can vary significantly based on the type of employer, with specialty practices such as dermatology and orthopedics typically providing higher wages than primary care settings. Factors contributing to this wage disparity include specialized skills, bilingual capabilities, and additional certifications—especially in high-demand areas like phlebotomy and EKG. To maximize earning potential, candidates should consider pursuing specializations or certifications recognized by organizations like AAMA or AMT, while also targeting employment at pharmacies or urgent care chains, known to offer competitive compensation.
More salary data for Greenville, SC:
Frequently Asked Questions
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Written by Emma Chen, CMA
Career Analyst
Emma has over 8 years of experience as a medical assistant. She has worked in both outpatient clinics and hospitals. Her expertise includes patient care and administrative support.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $44,860 for medical assistantsin the Greenville metropolitan area. A 4.97% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Source: BLS, OEWS, 7-year dataset (–). Per-city data from annual BLS metropolitan area surveys.
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 4.97%, derived from historical BLS wage trends for medical assistants (SOC 31-9092).
Compiled and verified by Emma Chen, CMA, a licensed medical assistant with 10+ years of clinical experience. · View source data at BLS.gov