Medical Assistant Salary in O'Fallon, MO: $41,200 (2026)
Quick Answer:A full-time medical assistant in O'Fallon, MO earns a median $41,200/year (≈ $19.81/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 31-9092). Once you factor in O'Fallon's price level (10% below national, BEA RPP 89.6), that paycheck buys what $45,982 would nationally. Nominal pay sits 0.1% below the Missouri state average.
Based on BLS state-level estimates · View source
In O'Fallon, Missouri, the projected median annual salary for medical assistants is $41,200 in 2026. This figure is below the national median of $47,961, reflecting a pay scale that varies considerably, with a range extending from $31,640 at the low end (P10) to $55,265 at the high end (P90). These estimates, derived from 2025 BLS data and adjusted for regional cost factors, highlight how local market dynamics influence compensation. As the healthcare industry continues to expand, the gap in earnings underscores the potential for medical assistants to bridge into higher-paying roles, such as licensed practical nurses (LPNs) or registered nurses (RNs), which can offer substantial long-term benefits.
About the O'Fallon Market
Salary estimated from Missouri average ($37,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $31,640 | $15.21 |
| Lower Range (P25) | $33,730 | $16.22 |
| Median (P50)(typical) | $41,200 | $19.81 |
| Upper Range (P75) | $44,155 | $21.22 |
| Top Earners (P90) | $55,265 | $26.57 |
Median Salary Position
14.1% below the national average
2026 Salary Percentile Distribution in O'Fallon
In O'Fallon, MO, the medical assistant salary spread from the 10th to 90th percentile is $23,625 (2026 est.). At $41,200, the local median is 14.1% below the national median of $47,961.
Salary Calculator
At 40 hours/week in O'Fallon: You'd be in the lower-middle range
How O'Fallon Medical Assistant Pay Compares
O'Fallon median: $41,200/year (2026)
| Compared To | Median Salary | O'Fallon Pays |
|---|---|---|
| Missouri Average | $41,241 | -0.10% less |
| National Average | $47,961 | -14.10% less |
Medical Assistants in O'Fallon, MO earn a median of $41,200 per year (2026 est.), which is 14.10% lower than the national median of $47,961 and 0.10% below the Missouri state average of $41,241.
Cost-of-Living Adjusted Salary
O'Fallon has a cost of living 10.40% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
O'Fallon, MO has a cost-of-living index of 89.6 (below the national average of 100). A medical assistant earning $41,200 nominally has purchasing power equivalent to $45,982 in an average-cost city — an effective 11.61% boost.
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2019 BLS Actual
$29,894
2025 BLS Actual
$39,249
2026 Current Est.
$41,200
2019–2027 Growth
+44.7%
Salary Trajectory for Medical Assistants in O'Fallon (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 4.97% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $29,894 | Actual |
| 2020 | $30,796 | Actual |
| 2021 | $31,947 | Actual |
| 2022 | $32,875 | Actual |
| 2023 | $36,079 | Actual |
| 2024 | $33,134 | Actual |
| 2025 | $39,249 | Actual |
| 2026(current) | $41,200 | Estimated |
| 2027 | $43,247 | Projected |
Based on 7 years of BLS OEWS data for the O'Fallon metropolitan area, the median medical assistant salary grew 31.3% from $29,894 (2019) to $39,249 (2025). At a 4.97% compound annual growth rate, salaries are projected to reach $43,247 by 2027 — a total increase of $13,353 (44.67%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the O'Fallon metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 4.97% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $31,640 – $33,730 |
| 3-5 years (Mid Career) | $33,730 – $41,200 |
| 5+ years (Experienced) | $41,200 – $44,155 |
| 10+ years (Top Earner) | $44,155 – $55,265 |
MA, CMA salary ranges estimated from BLS percentile data. Individual medical assistant compensation varies by employer, certifications, and specialization.
Medical Assistant Job Market in O'Fallon
Analyzing the local job market, O'Fallon reports approximately 22 medical assistants currently employed, indicating a modest but stable employment scene. With a cost-of-living index of 89.6, the purchasing power for medical assistant pay in O'Fallon is relatively favorable, although lower than the national average. Employers that typically offer higher salaries include specialty practices in dermatology and orthopedics, as well as urgent care chains like CityMD and MedExpress. The disparity in salaries can often be attributed to the type of healthcare setting, bilingual skills, and certification levels. Medical assistants keen on maximizing pay should consider enhancing their qualifications through additional certifications such as phlebotomy or EKG, and seek opportunities in high-demand specialty fields, as these moves can significantly elevate their earning potential in the O'Fallon market.
More salary data for O'Fallon, MO:
Frequently Asked Questions
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Written by Emma Chen, CMA
Career Analyst
Emma has over 8 years of experience as a medical assistant. She has worked in both outpatient clinics and hospitals. Her expertise includes patient care and administrative support.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $39,249 for medical assistantsin the O'Fallon metropolitan area. A 4.97% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for O'Fallon is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 4.97%, derived from historical BLS wage trends for medical assistants (SOC 31-9092).
Compiled and verified by Emma Chen, CMA, a licensed medical assistant with 10+ years of clinical experience. · View source data at BLS.gov